Background 

• Marine extremophiles and marine organism-associated bacteria have developed metabolic flexibility and biosynthetic machineries to assemble unique natural products 

Significance 

• Marine Natural Products have been designed by Nature to interact selectively with pharmacological targets and still inspire drug design 

Methodology 

• Multi-omics integration (genomics, metabolomics, culturomics) leads to discovery of novel lead compounds  

Aim 

• Harnessing the biosynthetic routes for natural products provides the tools to create sustainable sources of bioactive compounds in native and heterologous hosts