RNAissance, Inc - RNAissance: Pioneering RNA Therapeutics

Support

Ushering in a new era of medicine by expanding RNA biology into precision therapies that target RNA, RNA–protein interactions, and related pathways to unlock treatments for diseases that have eluded conventional approaches.

RNAissance: Reinventing RNA-Centered Therapeutics

At RNAissance, we believe a new scientific renaissance is upon us — one where RNA is more than a messenger but a strategic point of intervention. By expanding RNA therapeutics to include modulation of RNA–protein interactions and related targets, we are unlocking pathways that traditional approaches leave untouched. Our work builds on deep biological insight, combining computational biology with translational therapeutic design to change how disease is treated.

Our Story — Inspired by RNA, Driven by Discovery

Innovative formulation and engineering of delivery systems to enhance the stability and cellular uptake of RNA therapeutics.

Engineer developing a new process in cleanroom

RNA Delivery Systems Engineering

Development of RNA-based diagnostic tools for early detection and monitoring of diseases with high specificity.

RNA Diagnostics Solutions

Design and development of innovative RNA-based drugs targeting a variety of diseases, utilizing cutting-edge delivery technologies.

RNA Therapeutics Development

We design novel and unconventional therapeutics — from small molecules to engineered nucleic acids — guided by molecular structure, biological insight, and therapeutic intent. Precision and purpose drive every stage of our discovery process.

Rational Design of Next-Generation Medicines

We explore emerging RNA biology, including RNA–protein interactions, RNA metabolism, and system-level regulation across cancer biology, the gut–brain axis, aging, and the molecular boundary between cellular senescence and immortality.

New Mechanisms, New RNA Biology

We engineer therapeutics with defined purpose — adaptable across modalities and tailored for personalization. Our approach enables multi-functional and combinatorial therapies designed to address disease complexity rather than single targets.

Versatile Modalities for Personalized Medicine

Vision: A future of versatile, personalized RNA therapeutics.

Provisional Patent Filed: U.S. Application No. 63/901,790 (Filed Oct 19, 2025)

Structure of a 18-crown-ether. Rendered from "Crystal structure of EphA3 in complex with 18-Crown-6" (6IN0, res. 1.50 Å). Made with VMD and GIMP.

Pioneering a new era of RNA precision medicine: RNA at the core of transformative therapeutics.

RNAissance expands precision medicine — through oligonucleotides, small molecules, and RNA-protein modulation.

Precision therapies for diseases beyond conventional reach.

RNA–protein interactions as precision therapeutic targets: RNA/proteins dynamic complexes control health and disease.

Structure-based molecular control of disease, including RNA metabolism, is a core goal of RNAissance.

Colorful 3D molecular structures representing complex biological activities in a digital scientific illustration.

Gallery

Novel Coronavirus SARS-CoV-2 This scanning electron microscope image shows SARS-CoV-2 (orange)—also known as 2019-nCoV, the virus that causes COVID-19—isolated from a patient in the U.S., emerging from the surface of cells (green) cultured in the lab. Image captured and colorized at NIAID's Rocky Mountain Laboratories (RML) in Hamilton, Montana. Credit: NIAID https://www.flickr.com/photos/niaid/49531042907/

Colorful abstract molecular structures floating in a vibrant 3D space showcasing science and creativity

An artist’s illustration of artificial intelligence (AI). This image depicts how AI could assist in genomic studies and its applications. It was created by artist Nidia Dias as part of the Visualising AI project launched by Google DeepMind.

golden color mixed with pale greenish blue mixed in water tank and shot with high speed photography technique  

3D - Organic Plastic Shapes - Wallpaper - Background - 8K

An artist’s illustration of artificial intelligence (AI). This image explores how AI can be used advance biology and protein folding. It was created by Twistedpoly as part of the Visualising AI project launched by Google DeepMind.

Render of Benzopyrene or, better, Benzo[a]pyrene. Made with VMD.

Crystal structure of 2019-nCoV main protease in complex with an inhibitor N3. Made with VMD and GIMP.

Flu Hemagglutinin 3D print of hemagglutinin (HA), one of the proteins found on the surface of influenza virus that enables the virus to infect human cells. In this model, blue and purple denote areas where mutations can change the ability of the virus to attach to host cells and cause infection. For more information, visit the NIH 3D Print Exchange at 3dprint.nih.gov. Credit: NIH https://www.flickr.com/photos/niaid/14547505471/

Empowering health through RNA, igniting the Renaissance of medicine.

Discover the future of RNA therapeutics!

Young-Jin Cho, PhD

Founder &amp; CEO; Entrepreneur &amp; Dreamer

Jarnail Singh, PhD

Head of Biology;Interpreter

blank

Head of Medicinal ChemistryMolecular Architect

Young-Tae Lee, PhD

CSO;Truth-Seeker

The Team

Connect with RNAissance

Join Our CommunitySign up to receive updates on our research, collaborations, and opportunities to support RNA-centered innovation.

Stay Connected

Experimental services to measure RNA stability and degradation rates under various conditions for drug development or basic research.

One of the laboratories in the Clinical Research Center, National Institutes of Health (NIH).

RNA Stability and Degradation Assays

Expert guidance on designing RNA-based therapeutics tailored to your target disease, leveraging cutting-edge research and technology.

RNA Therapeutic Design Consulting

Design and synthesis of RNA aptamers for targeted binding to proteins, small molecules, or cells to suit your research needs.

Custom RNA Aptamer Development

We collaborate from the earliest stages of discovery to help beget new therapeutic projects. Through co-development partnerships, we contribute scientific insight, design strategy, and RNA expertise — with a shared goal of long-term value creation and profit sharing.

Beget the Project

We invite novel and unconventional ideas in RNA biology and therapeutic discovery. RNAissance partners with innovators to explore new mechanisms, validate concepts, and translate discovery into future opportunity.

Noble Research

Beyond discovery, RNAissance is committed to making life better. Through education, outreach, and collaborative initiatives, we aim to contribute to the scientific community and society at large — advancing knowledge, accessibility, and long-term societal well-being.

DNA Genotyping and Sequencing.
A technician works among a fleet of desktop genomic sequencing machines at the Cancer Genomics Research Laboratory, part of the National Cancer Institute's Division of Cancer Epidemiology and Genetics (DCEG). Creator:	Daniel Sone

Community Service

Support RNAissance

Supporting RNAissance includes staying informed, exploring partnerships, and expressing interest in future investment opportunities.RNAissance, Inc. is a for-profit corporation. This website does not constitute an offer to sell or solicit securities. Investment opportunities, if any, are offered only to qualified investors in compliance with applicable laws.

Support RNAissance

Beget the Project

Noble Research

Community Service

Support Our Work